| C.I.No | : | 50040 |
| Chemical Formula | : | C15H17ClN4 |
| CAS No. | : | 553-24-2 |
| Molecular Weight | : | 288.78 |
| Dye Content | : | ~60% |
| Absorption Max (EtOH 50%) | : | 539 – 544 nm |
| Absorptivity(1%,1cm) | : | >900 (on dry basis) |
| Transition Range | : | pH 6.8 – 8.0 Red – Orange |
| Loss On Drying (110° c.) | : | < 8% |
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.
2,3,5-Triphenyltetrazolium chloride has been used to stain heart tissue to measure the extent of acute lesion. It has also been used to stain brain tissue to check the size of infarct area.
Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase. Recently Cresol Red has been used as a pH sensitive indicator dye in nanoengineered optical urea biosensors films and hetero-core structured fiber optic pH sensor.
You cannot copy content of this page
